Dalelės iš dyzelinių dūmų kenkia sveikatai

Tas kenkimas pasireiškia ne tik kraujagyslių sistemai kenksmingais uždegimais, sukeliančiais aterosklerozę, bet ir kraujo indų susiaurėjimu [1]. Neveltui Prancūzijoje ir Jungtinėje Karalystėje pradedama uždrausti dyzelius miestuose. Taip reikia padaryti ir Lietuvoje. Kuo anksčiau, tuo geriau.






1. "Diesel exhaust particles (DEP) are associated with induction and exacerbation of cardiovascular
disorders through the production of harmful free radicals and initiation of pro-inflammatory
responses [1–3]. These events contribute to the resulting adverse health effects of DEP. Endothelial
dysfunction can be caused by diesel-induced mechanisms [4, 5]. Meanwhile, vasoconstriction
has been found in humans who inhaled ambient PM2.5 (particulate matter 2.5 μm)
for 2 h [6], and impaired vasodilatation appears 24 h after 1 h of DEP inhalation [5]. Moreover,
the water content of the mouse lung which causes epithelial fibrosis and disrupts vascular function
(increased 24 h after intratracheal instillation of DEPs or DEP extracts), which has been
suggested to cause an increase in pulmonary endothelial permeability [7]."

(Protective Effects of N-Acetyl Cysteine
against Diesel Exhaust Particles-Induced
Intracellular ROS Generates ProInflammatory
Cytokines to Mediate the
Vascular Permeability of Capillary-Like
Endothelial Tubes

Chia-Yi Tseng1,2, Jing-Fen Chang3
, Jhih-Syuan Wang3
, Yu-Jung Chang3
, Marion
K. Gordon4
, Ming-Wei Chao2,3*, PLOS One, 2015)