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2021 m. balandžio 10 d., šeštadienis

Blood Clots Linked to AstraZeneca Vaccine Stem From Rare Antibody Reaction


"New research has identified unusual antibodies that appear to have caused, in rare cases, serious and sometimes fatal blood clots in people who received the Covid vaccine made by AstraZeneca. The clotting problems were appearing at a rate of about one in 100,000 recipients.

Exactly why the rare reactions to the vaccine occurred is still a mystery.

Scientific teams from Germany and Norway found that people who developed the clots after vaccination had produced antibodies that activated their platelets, a blood component involved in clotting. The new reports add extensive details to what the researchers have already stated publicly about the blood disorder. It was a “likely possibility” that the people who developed the clotting disorder had some rare, unknown biological traits — what he called “individual co-factors” — that predisposed their immune systems to make powerful, misdirected antibodies in response to the vaccine. That “good news” for the general population, who do not have the co-factors.

Younger people appear more susceptible than older ones, but researchers say no pre-existing health conditions are known to predispose people to the rare reaction. That is worrisome, they say, because there is no way to tell if an individual is at high risk.

The European Medicines Agency, the regulator for the European Union, has emphasized repeatedly that the clotting disorder is rare, and that the vaccine’s benefits far outweigh its risks. But when a side effect has the potential to be devastating or fatal — like the blood clots in the brain linked to this vaccine — some regulators and segments of the public are finding that the risk is unacceptable, even if it is extremely rare."



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