There will be no Covid-19 deaths, the fear of coronavirus will end, everything will recover - Pfizer says Covid-19 tablets are 89% effective

"Pfizer Inc. said a preliminary look at study results found its experimental pill was highly effective at preventing people at high risk of severe Covid-19 from needing hospitalization or dying, the latest encouraging performance for an early virus treatment.

The company's drug cut the risk of hospitalization or death in study subjects with mild to moderate Covid-19 by about 89% if they took the pill within three days of diagnosis, Pfizer said Friday. The drug, called Paxlovid, was also found to be generally safe and well-tolerated in the early look at ongoing study results.

Pfizer plans to ask the Food and Drug Administration to authorize the drug's use this month, and the company could deliver doses this year, should regulators give a thumbs-up, Pfizer Chief Scientific Officer Mikael Dolsten said.

"It's stunning data," Dr. Dolsten said in an interview. "I feel very optimistic on a day like this. For everyone living in this pandemic, a new light of hope has turned on."

Pfizer has already begun to share with the FDA information about the drug needed for regulatory reviews, such as how it will be made, Dr. Dolsten said.

If authorized, there could be two Covid-19 pills that people could take before the end of the year. An antiviral from Merck & Co. and Ridgeback Biotherapeutics LP was cleared for use in the U.K. this week and is up for U.S. authorization.

Merck and Ridgeback said their pill, called molnupiravir, was found in an early look at study results to reduce the risk of hospitalization or death in people with mild to moderate Covid-19 by about 50%.

The advent of the promising antivirals indicates that Covid-19 drug research might be finally turning a corner after months of setbacks.

President Biden said the U.S. has secured "millions of doses" of Paxlovid. "The therapy would be another tool in our toolbox to protect people from . . . the worst outcomes of Covid," he said.

Doctors have struggled with few options for treating patients, especially early in the disease. The antiviral remdesivir, from Gilead Sciences Inc., is primarily used to treat hospitalized patients, and antibody treatments for recently diagnosed patients must be administered in doctors' offices, clinics and hospitals.

FDA clearance would expand Pfizer's role in the global pandemic response and in infectious disease more generally.

The drugmaker's Covid-19 vaccine, which it developed with BioNTech SE, has become the shot of choice around the world. This week, Pfizer raised its forecast for the vaccine's sales this year to $36 billion.

The antiviral pill could fetch $5 billion in yearly sales, Citi analysts estimated, with Pfizer signing supply contracts with countries and aiming to make doses available quickly. Paxlovid's higher efficacy, compared with Merck's drug, could also drive wider use.

Pfizer shares rose nearly 11% on Paxlovid's study results, while Merck and other companies that developed other Covid-19 treatments saw their shares fall.

Pfizer disclosed the results for Paxlovid in a news release after an early look at results for 1,219 subjects in a continuing Phase 2/3 study. The results haven't been published in a peer-reviewed scientific journal.

The drug was shown to be active against variants, including the highly contagious Delta, in laboratory testing, Pfizer said. The company plans to share in the future how the drug fared against variants in the study, a spokeswoman said.

Pfizer's pill is designed to stop the coronavirus from spreading in people by blocking activity of a key enzyme that the virus needs to replicate.

Patients would take 30 pills over five days. Twice a day over the course of treatment, they would take two pills of Paxlovid and one of another antiviral called ritonavir. Adding ritonavir slows the breakdown of the Pfizer drug, extending its duration to help fight the virus, the company said.

Pfizer researchers identified the drug in-house last year. Its late-stage study began in July and enrolled people deemed at high risk of becoming seriously ill with Covid-19. About half received the drug and a low dose of ritonavir twice a day for five days, while the other study subjects got a placebo.

Treatment began within five days after the participants developed Covid-19 symptoms.

A panel of independent experts, known as a data-safety monitoring committee, conducted the interim analysis and then shared its findings with Pfizer on Wednesday evening, Dr. Dolsten said.

In the interim analysis, three of the 389 subjects who received the drug within three days of showing symptoms were hospitalized through four weeks after beginning treatment, Pfizer said.

By comparison, 27 of the 385 subjects in the placebo group were either hospitalized or died, the company said, resulting in an efficacy rate of about 89%.

If subjects were treated within five days, the efficacy was about 85%, with six out of 607 subjects who received the drug becoming hospitalized, compared with 41 out of 612 people who received a placebo, according to Pfizer.

Through the four weeks, no subjects who received the Pfizer drug had died, compared with 10 deaths in the placebo group, according to Pfizer.

Pfizer is also testing the drug in people who are at low risk of developing severe Covid-19, including vaccinated people, and as a prophylactic to prevent the disease. Those results might come early next year, Pfizer has said.

Chief Executive Albert Bourla said Pfizer is increasing its manufacturing capabilities of the antiviral and has invested up to $1 billion to do so. "We are going to make sure that we make as many as possible as quickly as possible," he said in an interview.

Pfizer expects to manufacture 180,000 courses of treatment this year, and at least 50 million next year, including more than 21 million coming in the first half of the year.

If cleared for use, Pfizer said it would price the drug through a tiered system, in which low- and middle-income countries would pay less than wealthier ones. That approach is similar to how the company has priced its Covid-19 vaccine.

Wealthy nations such as the U.K. and Australia have said they have already reached supply deals. Pfizer said it is in talks with other countries.

Dr. Dolsten said Pfizer is exploring ways to ensure global access. Merck has entered into licensing agreements with makers of generic drugs and a nonprofit as part of an effort to expand access to molnupiravir." [1]

1. Covid-19 Pill Is 89% Effective, Pfizer Says
Hopkins, Jared S.  Wall Street Journal, Eastern edition; New York, N.Y. [New York, N.Y]. 06 Nov 2021: A.1.

 

Los Andželo arkivyskupas smerkia globalizmo augimą, antikrikščionišką „elito lyderių klasę“

„Los Andželo arkivyskupas José Gomezas pasmerkė sąmoningas pastangas „ištrinti krikščioniškąsias visuomenės šaknis ir nuslopinti bet kokią likusią krikščionišką įtaką“.

 

    Vaizdo kreipimesi į Madrido katalikų ir viešojo gyvenimo kongresą arkivyskupas Gomezas ketvirtadienį pareiškė, kad „mūsų šalyse išaugo elito lyderių klasė, kuri mažai domisi religija ir neturi tikro prisirišimo prie tautų, kuriose gyvena, ar su vietinių žmonių tradicijomis ar kultūromis“.

 

    „Ši grupė, atsakinga už korporacijas, vyriausybes, universitetus, žiniasklaidą, kultūros ir profesines institucijas, nori sukurti tai, ką galėtume pavadinti globalia civilizacija“, – perspėjo arkivyskupas.

 

    „Šioje elitinėje pasaulėžiūroje nereikia senamadiškų tikėjimo sistemų ir religijų“, – tęsė jis. „Iš tikrųjų, kaip jie mato, religija, ypač krikščionybė, tik trukdo visuomenei, kurią jie tikisi sukurti.

 

    Kritikuodamas siekį „atšaukti kultūrą“ ir „politinį korektiškumą“, Gomezas sakė, kad „dažnai atšaukiama ir taisoma perspektyvos, pagrįstos krikščioniškais įsitikinimais – apie žmogaus gyvenimą ir asmenį, apie santuoką, šeimą ir kt.

 

    Šiuolaikinėje visuomenėje „erdvė“, kurią Bažnyčiai ir tikintiems krikščionims leidžiama užimti, mažėja“, – apgailestavo jis. „Bažnyčios institucijos ir krikščionims priklausančios įmonės patiria vis daugiau iššūkių ir prie jų priekabiaujama“.

 

    „Tas pats pasakytina ir apie krikščionis, dirbančius švietimo, sveikatos apsaugos, valdžios ir kituose sektoriuose“, – pridūrė jis. „Teigiama, kad tam tikrų krikščioniškų įsitikinimų laikymasis kelia grėsmę kitų mūsų visuomenės grupių laisvėms ir net saugumui.

 

    Per koronaviruso pandemiją įsibėgėjo radikalios sekuliarizacijos projektas, kurio šaknys yra antikrikščioniškas, sakė arkivyskupas.

 

    „Manau, kad istorija pažvelgs atgal ir pamatys, kad ši pandemija nepakeitė mūsų visuomenės tiek, kiek pandemija paspartino tendencijas ir kryptis, kurios jau veikė“, – pastebėjo jis. „Dėl šios ligos ir mūsų visuomenės reakcijų socialiniai pokyčiai, kuriems galėjo vykti dešimtmečius, vyksta sparčiau.

 

    „Nauji socialiniai judėjimai ir ideologijos, apie kurias šiandien kalbame, buvo sėjami ir ruošiami daugelį metų mūsų universitetuose ir kultūros institucijose“, – teigė jis. „Tačiau dėl pandemijos ir socialinės izoliacijos sukeltos įtampos ir baimės, baltajam policininkui nužudžius neginkluotą juodaodį ir po to kilusių protestų mūsų miestuose šie judėjimai visiškai atsiskleidė mūsų visuomenėje.

 

    “. . . socialiniu teisingumu ar asmenine tapatybe pagrįstos politinių įsitikinimų sistemos atėjo užpildyti erdvę, kurią kažkada užėmė krikščioniškas tikėjimas ir praktika“, – sakė arkivyskupas.

 

    „Kad ir kaip vadintume šiuos judėjimus – „socialiniu teisingumu“, „pabudimu“, „tapatybės politika“, „intersekcionalumu“, „įpėdinio ideologija“ – jie teigia siūlantys tai, ką suteikia religija.

    „Šio judėjimo architektai siekia krikščioniškąją istoriją pakeisti „pabudimo istorija“ arba „socialinio teisingumo“ istorija“, – sakė jis.

 

    „Šiandieninės kritinės teorijos ir ideologijos yra labai ateistinės“, – pastebėjo Gomezas. „Jos neigia sielą, dvasinę, transcendentinę žmogaus prigimties dimensiją; arba jos mano, kad tai nėra svarbu žmogaus laimei“.

 

    Vietoj to, jos „sumažina tai, ką reiškia būti žmogumi, iki iš esmės fizinių savybių – mūsų odos spalvos, lyties, mūsų lyties sampratų, etninės kilmės ar padėties visuomenėje“, – pareiškė jis."

Dabar suprantate, kur taiko Broileris ir tvartelio gyventojas?

 

Los Angeles Archbishop Decries Rise of Globalism, Anti-Christian ‘Elite Leadership Class’

“Los Angeles Archbishop José Gomez has denounced a deliberate effort “to erase the Christian roots of society and to suppress any remaining Christian influences.”

In a powerful video address to the Congress on Catholics and Public Life in Madrid, Archbishop Gomez said Thursday that an “elite leadership class has risen in our countries that has little interest in religion and no real attachments to the nations they live in or to local traditions or cultures.”

“This group, which is in charge in corporations, governments, universities, the media, and in the cultural and professional establishments, wants to establish what we might call a global civilization,” the archbishop warned.

“In this elite worldview, there is no need for old-fashioned belief systems and religions,” he continued. “In fact, as they see it, religion, especially Christianity, only gets in the way of the society they hope to build.”

In his critique of “cancel culture” and “political correctness,” Gomez said that “often what is being canceled and corrected are perspectives rooted in Christian beliefs — about human life and the human person, about marriage, the family, and more.”

In modern society, “The ‘space’ that the Church and believing Christians are permitted to occupy is shrinking,” he lamented. “Church institutions and Christian-owned businesses are increasingly challenged and harassed.”

“The same is true for Christians working in education, health care, government, and other sectors,” he added. “Holding certain Christian beliefs is said to be a threat to the freedoms, and even to the safety, of other groups in our societies.”

The project of radical secularization, which is anti-Christian in its roots, has accelerated during the coronavirus pandemic, the archbishop said.

“I think history will look back and see that this pandemic did not change our societies as much as it accelerated trends and directions that were already at work,” he observed. “Social changes that might have taken decades to play out are now moving more rapidly in the wake of this disease and our societies’ responses.”

“The new social movements and ideologies that we are talking about today were being seeded and prepared for many years in our universities and cultural institutions,” he stated. “But with the tension and fear caused by the pandemic and social isolation, and with the killing of an unarmed black man by a white policeman and the protests that followed in our cities, these movements were fully unleashed in our society.”

“. . . political belief systems based on social justice or personal identity have come to fill the space that Christian belief and practice once occupied,” the archbishop said.

“Whatever we call these movements — ‘social justice,’ ‘wokeness,’ ‘identity politics,’ ‘intersectionality,’ ‘successor ideology’ — they claim to offer what religion provides.”
“The architects of this movement seek to replace the Christian story with “what we might call the ‘woke’ story or the ‘social justice’ story,” he said.

“Today’s critical theories and ideologies are profoundly atheistic,” Gomez observed. “They deny the soul, the spiritual, transcendent dimension of human nature; or they think that it is irrelevant to human happiness.”

Instead, they “reduce what it means to be human to essentially physical qualities — the color of our skin, our sex, our notions of gender, our ethnic background, or our position in society,” he declared."

Do you understand now where chicken little Gabrielius Landsbergis and the barn resident Vytautas Landsbergis are aiming? 

Atokiame Sibiro miestelyje dabar yra miniatiūrinė atominė elektrinė, kurią Rusijos valstybinė įmonė išbando, kaip naują gyvenamųjų namų šildymo modelį

"Du gamyklos branduoliniai raktoriai aušinami vandens kilpų serijomis. Kiekviename reaktoriuje pirmoji kilpa yra užteršta radioaktyviosiomis dalelėmis. Tačiau šis vanduo niekada nepalieka gamyklą. Per šilumokaičius jis perduoda šilumą, bet ne užterštą vandenį, kitoms kilpoms.

 

   Miestelyje viena iš šių kilpų yra vamzdžių, išeinančių iš gamyklos, išsišakojusių ir tiekiančių karštą vandenį į namus, sistema.

 

    Bendrovė reklamuoja daugybę saugos funkcijų. Gamykla gali atlaikyti mažo lėktuvo smūgį. Laivas, kuriame ji yra, veikia, kaip izoliacinė struktūra. Vanduo, cirkuliuojantis per pastatus, yra didesnio slėgio, nei aušinimo kontūre, iš kurio jis gauna šilumą gamykloje, teoriškai neleidžiant radiacijos nuotėkiui plisti į miestą.

 

    Rusija yra pirmoji, bet vargu ar išsiskirianti tokia mažų civilinių reaktorių plėtra. Šį mėnesį Prancūzijos prezidentas Emmanuelis Macronas pasiūlė išplėsti savo šalies platų branduolinį sektorių mažais reaktoriais, kaip dalį klimato kaitos problemos sprendimo. Kinija stato mažus plūduriuojančius reaktorius pagal Rusijos projektą."

Ir vėl tie rusai... Vis kažką naujo daro. Kur žiūri Kubilius ir tvartelio Patriarchas? Juk jie yra pas mus atsakingi už galutinį Rusijos sunaikinimą geitu laiku. O rusai sau šildosi ir juokiasi. Netvarka.