"Scientists have created the largest functional map of a brain to date -- a diagram of the wiring connecting 84,000 neurons as they fire off messages.
Using a piece of a mouse's brain about the size of a poppy seed, the researchers identified those neurons and traced how they communicated via branch-like fibers through a surprising 500 million junctions called synapses.
The massive dataset, published Wednesday by the journal Nature, marks a step toward unraveling the mystery of how human brains work. The data, assembled in a 3D reconstruction colored to delineate different brain circuitry, is open to scientists worldwide for additional research -- and for the simply curious to take a peek.
"It definitely inspires a sense of awe, just like looking at pictures of the galaxies," said Forrest Collman of the Allen Institute for Brain Science in Seattle, one of the project's leading researchers.
"You get a sense of how complicated you are," Collman said. "We're looking at one tiny part. . .of a mouse's brain and the beauty and complexity that you can see in these actual neurons and the hundreds of millions of connections between them."" [1]
1. U.S. News: With Mouse's Help, a Map Sheds Light on the Human Brain. Wall Street Journal, Eastern edition; New York, N.Y.. 10 Apr 2025: A2.
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