We hypothesized that driver mutations cause cancer. This idea is wrong.
"Premalignant lesions already harbour cancer driver mutations." [1]
Premalignant lesions are benign.
1. Tumour heterogeneity and evolutionary dynamics in colorectal cancer. Dedrick Kok Hong Chan & Simon James Alexander Buczacki. Oncogenesis, volume 10, Article number: 53 (2021), Published: 16 July 2021
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